Monthly Archive: May 2012

May 24

Could the Recent Change in Availability of Death Master File Data Affect Your Research?

Cancer epidemiologists and other health researchers have long relied on the Social Security Administration’s (SSA) Death Master File (DMF) data for determining the vital status of participants.  Researchers find the DMF helpful in their observational studies and prevention and clinical trials because it is a single, centralized source of information across the 50 states, low …

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May 01

A Tale of Two Genomes: Mitochondrial Genomics and Cancer Risk

Mitochondria play important roles in cellular energy metabolism, free radical generation, and apoptosis, and as a result, mitochondrial variations that affect these functions may contribute to the development and progression of cancer. In most cases, reactive oxygen species and DNA adducts induce mitochondrial mutations. Other agents that may result in mutations include radiation, infectious agents, and …

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